BIOGRAPHY

Marc Pignot

  • Marc Pignot

    Chief Strategy Officer, Head of Real-World Evidence & Safety Data Analytics

Dr. Marc Pignot joined ZEG Berlin to lead the implementation and development of Real-World Evidence & Safety Data Analytics.

Marc has more than 20 years of experience in the pharmaceutical and CRO business. As Chief Strategy Officer, he is establishing a strong secondary data stream to complement and combine with ZEG Berlin’s long-established primary data business. Real-World Evidence and services bridge the growing need for leading-edge secondary data collection with ZEG Berlin’s classical studies for post-authorization, safety, and effectiveness.

Marc Pignot served as Director of Real-World Evidence, and global consulting at Kantar Health, and as a Director at Kendle, now Syneos Health, a global CRO. He was responsible for conducting global clinical trials and Late Phase programs in the main therapeutic areas.

He also worked on Diagnostic Imaging and Medical Device Studies at Amersham Health and GE Healthcare. Before moving to clinical research, Marc worked with Aventis Pharmaceutical’s global research center focusing on functional genomics and proteomics.

Marc Pignot holds a PhD in Bio-Organic Chemistry from the Max Planck Institute of Molecular Physiology and completed postdoctoral training in nucleic acid chemistry at the University of Frankfurt/Scripps Research Institute (La Jolla).

PUBLICATIONS

A Real-World Evaluation of Brain Imaging in Patients with Advanced Non-Small Cell Lung Cancer: Insights from a German Claims Data Analysis Atmaca Akin, Grohé Christian, Klinghardt Moritz, Kossack Nils, Marc Pignot, Schuh Roxana Oncol Res Treat. 2025; 10.1159/000547215. https://doi.org/10.1159/000547215
Epidemiology and burden of mild/moderate versus high myopia in Germany: A claims data analysis. Tarcyane Barata Garcia, Kossack Nils, Marc Pignot, Mohammed Dagher, Schuster Alexander K., Wielink Kun Shi-van Acta Ophthalmologica. 2025; 10.1111/aos.17589.
Real-world psoriasis treatment patterns and disease burden in Germany, with a focus on biologics and apremilast: data from a German statutory health insurance database Pinter Andreas, Schulte Marcus, Kossack Nils, Marc Pignot, Michael Schultze, Feldhus Andrea JME: Journal of Medical Economics. 2025; VOL. 28, NO. 1, 207-220. 10.1080/13696998.2025.2452054. https://doi.org/10.1080/13696998.2025.2452054
The Impact of Systemic Lupus Erythematosus Flares on Clinical and Economic Outcomes: The CHAMOMILE Claims Database Study in Germany Ding Bo, Marc Pignot, Garal-Pantaler Elena, Villinger Beate, Schefzyk Sebastian, Desta Barnabas, Stirnadel-Farrant Heide, Schwarting Andreas Rheumatol Ther. 2024; 10.1007/s40744-023-00635-0. https://doi.org/10.1007/s40744-023-00635-0
Unveiling the untreated: development of a database algorithm to identify potential Fabry disease patients in Germany Hilz M., Lyn N, Marczykowski F., Werner B., Marc Pignot, Ponce E, Bender J., Edigkaufer M., Das Mahapatra P. Orphanet J Rare Dis. 2024; 10.1186/s13023-024-03258-y. https://doi.org/10.1186%2Fs13023-024-03258-y
Comorbidities, healthcare resource utilization & treatment pattern among patients with prurigo nodularis, compared to a benchmark in Germany: A real-world evidence claims data study Ständer Sonja, Ketz Miriam, Akumo Divine, Kossack Nils, Marc Pignot, Chavda Rajeev, Gabriel Sylvie J Eur Acad Dermatol Venerol. 2023; 1-12. 10.1111/jdv.19700. http://doi.org/10.1111/jdv.19700
Clinical Characteristics, Health Care Resource Utilization, and Costs Associated With Flares in Patients With Systemic Lupus Erythematosus in Germany Ding Bo, Marc Pignot, Garal-Pantaler Elena, Villinger Beate, Desta Barnabas, Schmidt Katharina, Golam Sarowar, Stirnadel-Farrant Heide, Schwarting Andreas Ann. Rheum. Dis. – EULAR 2022 Annual European Congress of Rheumatology, June 1–4. 2022; http://dx.doi.org/10.1136/annrheumdis-2022-eular.899
Prevalence of lupus nephritis among patients with systemic lupus erythematosus in Germany N Hunnicutt Jake, Michael Schultze, Garal-Pantaler Elena, Marc Pignot, Georgiou Mary Elizabeth, Gairy Kerry Nephrology Dialysis Transplantation, Volume 37, Issue Supplement_3, May. 2022; 10.1093/ndt/gfac071.036. https://doi.org/10.1093/ndt/gfac071.036
Evaluation of Treatment Patterns of Fabry Disease Utilizing Medical Claims Analyses of a German Sickness Fund Database Hilz M., Das Mahapatra P., Fan Q., Marczykowski F., Werner B., Marc Pignot, Bender J., Punekar R., Hamed A., Edigkaufer M. Value in Health, VOLUME 23. 2020; SUPPLEMENT 1, S347. 10.1016/j.jval.2020.04.1321. https://doi.org/10.1016/j.jval.2020.04.1321
Real-World Cost Difference in Patients With Psoriasis Initiating Apremilast vs. Secukinumab After Conventional Systemic Therapy Using German Sickness Fund Data Kossack Nils, Schoenfelder T., Michael Schultze, Marc Pignot, Mehta S., Nazareth T., Walzer S. DDK KOMPAKT 2020. JDDG Volume 18 Issue S1. 2020. 2020; 10.1111/ddg.14021. https://doi.org/10.1111/ddg.14021
Using Data from a Sickness Fund Claims Database to Assess the Treatment Patterns and Healthcare Resource Utilization among Patients with Metastatic Renal Cell Carcinoma in Germany Bögemann Martin, Zagorska Aleksandra, Akumo Divine, El Hadad Laila, Marc Pignot Urologia Internationalis. 2020; 10.1159/000509973. https://www.karger.com/Article/Abstract/509973
Cardiorenal disease is the most common first CV manifestation in type 2 diabetes and associated with increased mortality: a large multinational observational study Birkeland Kåre I., Bodegard Johan, Eriksson Jan W., Norhammar Anna, Thuresson Marcus, Marc Pignot, Garal-Pantaler Elena, Yajima Toshitaka, Komuro Issei, Kadowaki Takashi EASD Congress. 2019; https://www.easd.org/virtualmeeting/home.html#!resources/cardiorenal-disease-is-the-most-common-first-cv-manifestation-in-type-2-diabetes-and-associated-with-increased-mortality-a-large-multinational-observational-study-c4476072-a6ca-440f-9e97-670ffa516ceb
Cardiorenal disease is the most common first CV manifestation in type 2 diabetes and associated with increased mortality: a large multinational observational study Birkeland Kåre I., Bodegard Johan, Eriksson Jan W., Norhammar Anna, Thuresson Marcus, Marc Pignot, Garal-Pantaler Elena, Yajima Toshitaka, Komuro Issei, Kadowaki Takashi European Association for the Study of Diabetes 55th Annual Meeting. 2019; https://www.abstractsonline.com/pp8/#!/7895/presentation/1302

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